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MELANOCYTE-STIMULATING HORMONES
Descriptors Found:
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DeCS
Descriptor
English
:
Melanocyte-Stimulating Hormones
Descriptor
Spanish
:
Hormonas Estimuladoras de los Melanocitos
Descriptor
Portuguese
:
Hormônios Estimuladores de Melanócitos
Synonyms
English
:
MSH
Melanotropin
Tree Number:
D06.472.699.327.935.531.750
D06.472.699.631.525.600.531.750
D12.644.400.400.935.531.750
D12.644.400.460
D12.644.548.365.935.531.750
D12.644.548.691.525.690.531.750
D12.776.641.650.405.935.531.750
D12.776.641.650.460
Definition
English
:
Peptides with the ability to stimulate pigmented
cells
MELANOCYTES
in
mammals
and
MELANOPHORES
in lower
vertebrates
. By stimulating the synthesis and distribution of MELANIN in these pigmented
cells
, they increase coloration of
skin
and other tissue. MSHs, derived from
pro-opiomelanocortin
(POMC), are produced by
MELANOTROPHS
in the INTERMEDIATE LOBE OF PITUITARY;
CORTICOTROPHS
in the ANTERIOR LOBE OF PITUITARY, and the hypothalamic
neurons
in the
ARCUATE NUCLEUS.
Pharmacological Action:
Hormones
History Note
English
:
2006(1963)
Allowable Qualifiers
English
:
administration & dosage
adverse effects
agonists
antagonists & inhibitors
analysis
biosynthesis
blood
cerebrospinal fluid
chemistry
classification
chemical synthesis
contraindications
drug effects
deficiency
diagnostic use
economics
genetics
history
immunology
isolation & purification
metabolism
pharmacology
physiology
pharmacokinetics
poisoning
radiation effects
supply & distribution
secretion
standards
toxicity
therapeutic use
urine
Record Number:
23523
Unique Identifier:
D009074
Occurrence in VHL
:
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